RORγt-IN-9a
Modify Date: 2025-09-10 19:07:02
RORγt-IN-9a structure
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Common Name | RORγt-IN-9a | ||
|---|---|---|---|---|
| CAS Number | 1426803-07-7 | Molecular Weight | 518.328 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H16Cl2F3NO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RORγt-IN-9aA potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice. |
| Name | RORγt-IN-9a |
|---|
| Description | A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice. |
|---|---|
| References | References 1. Wang Y, et al. ACS Med Chem Lett. 2015 May 26;6(7):787-92. View Related Products by Target ROR |
| Molecular Formula | C22H16Cl2F3NO4S |
|---|---|
| Molecular Weight | 518.328 |
| InChIKey | AKJULTWNHWSAFM-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 |