1426803-07-7
1426803-07-7 structure
- Name: RORγt-IN-9a
- Chemical Name: RORγt-IN-9a
- CAS Number: 1426803-07-7
- Molecular Formula: C22H16Cl2F3NO4S
- Molecular Weight: 518.328
- Create Date: 2020-01-12 12:00:45
- Modify Date: 2025-09-10 19:07:02
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A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice.
| Name | RORγt-IN-9a |
|---|
| Description | A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice. |
|---|---|
| References | References 1. Wang Y, et al. ACS Med Chem Lett. 2015 May 26;6(7):787-92. View Related Products by Target ROR |
| Molecular Formula | C22H16Cl2F3NO4S |
|---|---|
| Molecular Weight | 518.328 |