las191859

Modify Date: 2024-04-08 09:12:02

las191859 structure	Common Name	las191859
	CAS Number	1420071-13-1	Molecular Weight	459.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₄F₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of las191859

LAS191859 is an orally active, potent and selective CRTh2 antagonist with an IC50 of 9.58 nM against human CRTh2. LAS191859 can be used for the research of chronic asthma[1].

Name	las191859

Description	LAS191859 is an orally active, potent and selective CRTh2 antagonist with an IC50 of 9.58 nM against human CRTh2. LAS191859 can be used for the research of chronic asthma[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
Target	IC50: 7.6 nM (guinea pig CRTh2), 9.58 nM (human CRTh2), 14 nM (rat CRTh2), 15.5 nM (mouse CRTh2)[1]
References	[1]. Calbet M, et al. Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy. Pharmacol Res. 2016 Sep;111:208-216.

Molecular Formula	C₂₄H₂₄F₃N₃O₃
Molecular Weight	459.46

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LAS191859
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Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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las191859

Use of las191859

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las191859 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.