2-Cyanopyrimidine structure
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Common Name | 2-Cyanopyrimidine | ||
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CAS Number | 14080-23-0 | Molecular Weight | 105.097 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 250.7±23.0 °C at 760 mmHg | |
Molecular Formula | C5H3N3 | Melting Point | 40-44 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 97.2±7.8 °C | |
Symbol |
GHS06 |
Signal Word | Danger |
Use of 2-Cyanopyrimidine2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1]. |
Name | 2-Cyanopyrimidine |
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Synonym | More Synonyms |
Description | 2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1]. |
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Related Catalog | |
Target |
IC50: 170 nM (cysteine protease cathepsin K)[1] |
In Vitro | 2-Cyanopyrimidine is a 2-cyano-4-cyclohexylamino-pyrimidine derivative. Cathepsin K is a lysosomal cysteine protease[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 250.7±23.0 °C at 760 mmHg |
Melting Point | 40-44 °C(lit.) |
Molecular Formula | C5H3N3 |
Molecular Weight | 105.097 |
Flash Point | 97.2±7.8 °C |
Exact Mass | 105.032700 |
PSA | 49.57000 |
LogP | -0.31 |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.541 |
Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H301-H317 |
Precautionary Statements | P280-P301 + P310 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xn:Harmful |
Risk Phrases | R22;R37/38;R41;R43 |
Safety Phrases | S26-S36/37/39 |
RIDADR | 3276 |
WGK Germany | 3 |
HS Code | 2933599090 |
HS Code | 2933599090 |
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Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.
Nat. Commun. 6 , 8580, (2015) Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ... |
2-Cyanopyrimidine |
NaMe: 2-CyanopyriMidine |
Pyrimidin-2-carbonitril |
2-Cynopyrimidine |
2-CPY |
pyrimidin-2-carbonitrile |
MFCD00160513 |
2CPM |
2-Pyrimidinecarbonitrile |
Pyrimidine-2-carbonitrile |
2-cyanpyrimidine |
2-pyrimidinenitrile |