2-Cyanopyrimidine structure
|
Common Name | 2-Cyanopyrimidine | ||
|---|---|---|---|---|
| CAS Number | 14080-23-0 | Molecular Weight | 105.097 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 250.7±23.0 °C at 760 mmHg | |
| Molecular Formula | C5H3N3 | Melting Point | 40-44 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 97.2±7.8 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of 2-Cyanopyrimidine2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1]. |
| Name | 2-Cyanopyrimidine |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 170 nM (cysteine protease cathepsin K)[1] |
| In Vitro | 2-Cyanopyrimidine is a 2-cyano-4-cyclohexylamino-pyrimidine derivative. Cathepsin K is a lysosomal cysteine protease[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 250.7±23.0 °C at 760 mmHg |
| Melting Point | 40-44 °C(lit.) |
| Molecular Formula | C5H3N3 |
| Molecular Weight | 105.097 |
| Flash Point | 97.2±7.8 °C |
| Exact Mass | 105.032700 |
| PSA | 49.57000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.541 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H317 |
| Precautionary Statements | P280-P301 + P310 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R37/38;R41;R43 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| HS Code | 2933599090 |
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.
Nat. Commun. 6 , 8580, (2015) Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ... |
| 2-Cyanopyrimidine |
| NaMe: 2-CyanopyriMidine |
| Pyrimidin-2-carbonitril |
| 2-Cynopyrimidine |
| 2-CPY |
| pyrimidin-2-carbonitrile |
| MFCD00160513 |
| 2CPM |
| 2-Pyrimidinecarbonitrile |
| Pyrimidine-2-carbonitrile |
| 2-cyanpyrimidine |
| 2-pyrimidinenitrile |