PF 06273340

Modify Date: 2024-01-12 11:28:17

PF 06273340 Structure
PF 06273340 structure
Common Name PF 06273340
CAS Number 1402438-74-7 Molecular Weight 479.919
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C23H22ClN7O3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of PF 06273340


PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1].

 Names

Name I136775ABW
Synonym More Synonyms

 PF 06273340 Biological Activity

Description PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1].
Related Catalog
Target

TRK

References

[1]. Skerratt SE, et al. The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C23H22ClN7O3
Molecular Weight 479.919
Exact Mass 479.147278
LogP 0.92
Index of Refraction 1.711

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
RIDADR NONH for all modes of transport

 Synonyms

PF-06273340
2-Pyridineacetamide, N-[5-[[2-amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-
N-(5-{[2-Amino-7-(1-hydroxy-2-methyl-2-propanyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}-3-pyridinyl)-2-(5-chloro-2-pyridinyl)acetamide
I136775ABW
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