5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone

Modify Date: 2024-01-04 13:13:57

5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone structure	Common Name	5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
	CAS Number	139756-21-1	Molecular Weight	312.366
	Density	1.3±0.1 g/cm3	Boiling Point	504ºC at 760 mmHg
	Molecular Formula	C₁₇H₂₀N₄O₂	Melting Point	141-145ºC(lit.)
	MSDS	Chinese USA	Flash Point	258.6ºC
	Symbol	GHS07	Signal Word	Warning

Use of 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone

PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1].

Name	5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Synonym	More Synonyms

Description	PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Others
Target	PDE5:5 nM (IC50) PDE1:300 nM (IC50)
In Vitro	PDE5-IN-7 (compound 15, Desild) can be detected and isolated from Sildenafil (HY-15025) derivatives[2].

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933990090

Precursor 10
CAS#:139756-03-9 4-(2-Ethoxybenz... CAS#:613-69-4 2-Ethoxybenzaldehyde CAS#:139756-02-8 4-Amino-1-methy... CAS#:42926-52-3 2-Ethoxybenzoyl...
CAS#:139756-01-7 1-METHYL-4-NITR... CAS#:36983-31-0 Ethyl 2,4-dioxo... CAS#:139755-99-0 1-Methyl-3-prop... CAS#:133261-07-1 1-Methyl-3-prop...
CAS#:139756-00-6 1-METHYL-4-NITR... CAS#:134-11-2 2-Ethoxybenzoic acid
DownStream 6
CAS#:371959-09-0 Norneosildenafil CAS#:479074-06-1 5-(2-ethoxyphen... CAS#:1058653-74-9 5-[5-(2-Chloroa... CAS#:139755-85-4 Hydroxyhomo Sil...
CAS#:139755-83-2 Sildenafil CAS#:139756-22-2 4-Ethoxy-3-(1-m...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

5-(2-ethoxyphenyl)-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one

5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-(2-ethoxyphenyl)-1,6-dihydro-1-methyl-3-propyl-

5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

5-(2-Ethoxyphenyl)-l-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolol- 4,3-dipyrimidin-7-one

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Tianfu Chem 5-(2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO[4,3-D]-7-PYRIMIDINONE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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