- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
- Price: ￥4708.0/10g ￥1128.0/2g
- Purity: 97.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Tianfu Chem 5-(2-ETHOXYPHENYL)-1-METHYL-3-N-PROPYL-1,6-DIHYDRO-7H-PYRAZOLO[4,3-D]-7-PYRIMIDINONE
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
139756-21-1
139756-21-1 structure
- Name: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone
- Chemical Name: 5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
- CAS Number: 139756-21-1
- Molecular Formula: C17H20N4O2
- Molecular Weight: 312.366
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2018-12-28 06:54:06
- Modify Date: 2025-08-25 22:54:09
-
PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1].
| Name | 5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one |
|---|---|
| Synonyms |
5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
5-(2-ethoxyphenyl)-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one 5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-(2-ethoxyphenyl)-1,6-dihydro-1-methyl-3-propyl- 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 5-(2-Ethoxyphenyl)-l-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolol- 4,3-dipyrimidin-7-one |
| Description | PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1]. |
|---|---|
| Related Catalog | |
| Target |
PDE5:5 nM (IC50) PDE1:300 nM (IC50) |
| In Vitro | PDE5-IN-7 (compound 15, Desild) can be detected and isolated from Sildenafil (HY-15025) derivatives[2]. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 504ºC at 760 mmHg |
| Melting Point | 141-145ºC(lit.) |
| Molecular Formula | C17H20N4O2 |
| Molecular Weight | 312.366 |
| Flash Point | 258.6ºC |
| Exact Mass | 312.158630 |
| PSA | 72.80000 |
| LogP | 2.38 |
| Vapour Pressure | 2.75E-10mmHg at 25°C |
| Index of Refraction | 1.632 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
| Precursor 10 | |
|---|---|
| DownStream 6 | |
![5-(2-ethoxyphenyl)-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione structure](https://image.chemsrc.com/caspic/336/479074-06-1.png)
![5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one structure](https://image.chemsrc.com/caspic/320/1058653-74-9.png)
![4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzene-1-sulfonyl chloride structure](https://image.chemsrc.com/caspic/273/139756-22-2.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |