Azemiopsin

Modify Date: 2025-08-25 17:45:01

Azemiopsin structure	Common Name	Azemiopsin
	CAS Number	1391936-86-9	Molecular Weight	2540.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁₈H₁₇₄N₃₈O₂₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azemiopsin

Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR[1].

Name	Azemiopsin

Description	Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: 0.18 μM (T. californica nAChR), 22 μM (Human α7 nAChR), 63 μM (L. stagnalis AChBP), 230 μM (A. californica AChBP)[1]
References	[1]. Utkin YN, et al. Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem. 2012 Aug 3;287(32):27079-86.

Molecular Formula	C₁₁₈H₁₇₄N₃₈O₂₆
Molecular Weight	2540.88

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Azemiopsin

Use of Azemiopsin

Names

Azemiopsin Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.