PF 04628935
Modify Date: 2025-08-26 17:30:16
PF 04628935 structure
|
Common Name | PF 04628935 | ||
|---|---|---|---|---|
| CAS Number | 1383719-97-8 | Molecular Weight | 496.03 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C24H26ClN7OS | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of PF 04628935PF-04628935 (compound 10n) is a potent ghrelin receptor inverse agonist, with an IC50 of 4.6 nM. PF-04628935 exhibits oral bioavailability of 43% in rats and shows reasonable penetration into the brain. PF-04628935 can be used for stress and anxiety research[1][2]. |
| Name | 1-{2-[2-Chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7-diazaspiro[3.5]non-7-yl}-2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)ethanone |
|---|---|
| Synonym | More Synonyms |
| Description | PF-04628935 (compound 10n) is a potent ghrelin receptor inverse agonist, with an IC50 of 4.6 nM. PF-04628935 exhibits oral bioavailability of 43% in rats and shows reasonable penetration into the brain. PF-04628935 can be used for stress and anxiety research[1][2]. |
|---|---|
| Related Catalog | |
| Target |
GHSR1a:4.6 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C24H26ClN7OS |
| Molecular Weight | 496.03 |
| Exact Mass | 495.160797 |
| LogP | 4.14 |
| Index of Refraction | 1.764 |
| RIDADR | NONH for all modes of transport |
|---|
| 1-{2-[2-Chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7-diazaspiro[3.5]non-7-yl}-2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)ethanone |
| Ethanone, 1-[2-[[2-chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)- |