chelidamic acid structure
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Common Name | chelidamic acid | ||
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CAS Number | 138-60-3 | Molecular Weight | 183.118 | |
Density | 1.7±0.1 g/cm3 | Boiling Point | 428.3±45.0 °C at 760 mmHg | |
Molecular Formula | C7H5NO5 | Melting Point | 267 °C (dec.)(lit.) | |
MSDS | Chinese USA | Flash Point | 212.8±28.7 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of chelidamic acidChelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. |
Name | Chelidamic acid |
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Synonym | More Synonyms |
Description | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. |
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Related Catalog | |
Target |
Ki: 33 μM (Glutamate decarboxylase)[3]. |
In Vitro | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton[1]. Chelidamic acid has good coordination ability with noble metal ions[2]. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM[3]. |
References |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 428.3±45.0 °C at 760 mmHg |
Melting Point | 267 °C (dec.)(lit.) |
Molecular Formula | C7H5NO5 |
Molecular Weight | 183.118 |
Flash Point | 212.8±28.7 °C |
Exact Mass | 183.016769 |
PSA | 107.46000 |
LogP | -1.43 |
Vapour Pressure | 0.0±2.2 mmHg at 25°C |
Index of Refraction | 1.635 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi:Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933399090 |
~92% chelidamic acid CAS#:138-60-3 |
Literature: Horvath, Gyoergy; Rusa, Cristian; Koentoes, Zoltan; Gerencser, Janos; Huszthy, Peter Synthetic Communications, 1999 , vol. 29, # 21 p. 3719 - 3731 |
Precursor 1 | |
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DownStream 10 | |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase.
Biochem. Pharmacol. 34 , 4145-4150, (1985) Twenty conformationally restricted analogues of glutamate including benzoic acids, hydroxy-benzoic acids, pyridine dicarboxylic acids, and pyran dicarboxylic acids were tested as inhibitors of glutama... |
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Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives.
Anticancer Drug Des. 13(8) , 837-55, (1998) We have explored the potential antitumour activity of DNA-intercalating free radical generators based on compounds constructed from 9-anilinoacridine and chelidamic acid as an iron (II) binding centre... |
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[Use of the radial hemolysis reaction for titrating antirabies sera].
Vopr. Virusol. 29(3) , 360-1, (1984)
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Pd(OH)2/C |
chelidamic acid |
4-Hydroxypyridine-2,6-dicarboxylic Acid Monohydrate |
4-oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid |
MFCD00066478 |
4-Hydroxy-2,6-pyridinedicarboxylic acid |
4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid |
4-PYRIDONE-2,6-DICARBOXYLIC ACID |
1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid |
.HELIDAMIC AICD |
2,6-Pyridinedicarboxylic acid, 1,4-dihydro-4-oxo- |
CHELIDAMIC ACID HYDRATE |
Chelidamaic acid |
Chelidamic Acid Monohydrate |
Chelidamic aicd |
2,6-Pyridinedicarboxylic acid, 4-hydroxy- |
Ammox-chelidonic acid |
4-Hydroxypyridine-2,6-dicarboxylic acid |
chelidamic acid approx. |
EINECS 205-335-8 |
4-hydroxyl-pyridine-2,6-dicarboxylic acid |