(S,S)-BMS-984923

Modify Date: 2025-08-25 18:11:56

(S,S)-BMS-984923 structure	Common Name	(S,S)-BMS-984923
	CAS Number	1375752-77-4	Molecular Weight	374.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₅ClN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S,S)-BMS-984923

(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor[1]. BMS-984923 is a potent mGluR5 silent allosteric modulator[2].

Name	(S,S)-BMS-984923

Description	(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor[1]. BMS-984923 is a potent mGluR5 silent allosteric modulator[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Andrew P. Degnan, et al. Oxazolidinones as modulators of mglur5. WO2012064603A1. [2]. Laura T Haas, et al. Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. Cell Rep. 2017 Jul 5;20(1):76-88.

Description

(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor[1]. BMS-984923 is a potent mGluR5 silent allosteric modulator[2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

References

[1]. Andrew P. Degnan, et al. Oxazolidinones as modulators of mglur5. WO2012064603A1.

[2]. Laura T Haas, et al. Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. Cell Rep. 2017 Jul 5;20(1):76-88.

Molecular Formula	C₂₂H₁₅ClN₂O₂
Molecular Weight	374.82

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(S,S)-BMS-984923

Use of (S,S)-BMS-984923

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(S,S)-BMS-984923 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.