1374107-46-6

Modify Date: 2025-08-29 13:32:41

1374107-46-6 Structure
1374107-46-6 structure
Common Name 1374107-46-6
CAS Number 1374107-46-6 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1374107-46-6


THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe[1].

 Names

Name 1374107-46-6
Synonym More Synonyms

 1374107-46-6 Biological Activity

Description THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe[1].
Related Catalog
References

[1]. Nobuyuki Okamura, et al. Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease. J Nucl Med. 2013 Aug;54(8):1420-7.

 Chemical & Physical Properties

No Any Chemical & Physical Properties

 Synonyms

C20H21FN2O2
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