2'-arafluorozebularine

Modify Date: 2025-08-26 17:48:12

2'-arafluorozebularine structure	Common Name	2'-arafluorozebularine
	CAS Number	136675-88-2	Molecular Weight	230.19
	Density	1.67g/cm3	Boiling Point	452.9ºC at 760mmHg
	Molecular Formula	C₉H₁₁FN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	227.7ºC

Use of 2'-arafluorozebularine

2′-Deoxy-2′-fluoro-4-deoxy-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone
Synonym	More Synonyms

Description	2′-Deoxy-2′-fluoro-4-deoxy-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.67g/cm3
Boiling Point	452.9ºC at 760mmHg
Molecular Formula	C₉H₁₁FN₂O₄
Molecular Weight	230.19
Flash Point	227.7ºC
Exact Mass	230.07000
PSA	84.58000
Vapour Pressure	4.16E-10mmHg at 25°C
Index of Refraction	1.644
InChIKey	WQIKHPATWLOZFO-ULAWRXDQSA-N
SMILES	O=c1ncccn1C1OC(CO)C(O)C1F