ONO-4059
Modify Date: 2025-08-24 18:10:12
ONO-4059 structure
|
Common Name | ONO-4059 | ||
|---|---|---|---|---|
| CAS Number | 1351636-18-4 | Molecular Weight | 454.481 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 672.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C25H22N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 360.2±34.3 °C | |
Use of ONO-4059Tirabrutinib (ONO-4059) is a highly selective, orally bioavailable BTK inhibitor with an IC50 of 2.2 nM. |
| Name | tirabrutinib |
|---|---|
| Synonym | More Synonyms |
| Description | Tirabrutinib (ONO-4059) is a highly selective, orally bioavailable BTK inhibitor with an IC50 of 2.2 nM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.2 nM (BTK)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 672.0±65.0 °C at 760 mmHg |
| Molecular Formula | C25H22N6O3 |
| Molecular Weight | 454.481 |
| Flash Point | 360.2±34.3 °C |
| Exact Mass | 454.175354 |
| LogP | 2.31 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.700 |
| InChIKey | SEJLPXCPMNSRAM-GOSISDBHSA-N |
| SMILES | CC#CC(=O)N1CCC(n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1 |
| tirabrutinib |
| MFCD28386296 |
| 8H-Purin-8-one, 6-amino-7,9-dihydro-9-[(3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)- |
| UNII:LXG44NDL2T |
| 6-Amino-9-[(3R)-1-(2-butynoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one |
| ONO-BKT |
| ONO-4059 |