GE 2270A
Modify Date: 2025-08-25 15:44:35
GE 2270A structure
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Common Name | GE 2270A | ||
|---|---|---|---|---|
| CAS Number | 134861-34-0 | Molecular Weight | 1290.52000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C56H55N15O10S6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GE 2270AGE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2]. |
| Name | Mdl 62879 |
|---|
| Description | GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.4 μM (poly(U)-directed poly(Phe) synthesis)[2] |
| In Vitro | GE 2270A (0.01-100 mg/L) inhibits poly(U)-directed poly(Phe) synthesis in cell-free systems with an IC50 value of 0.12 mg/L[1]. GE 2270A (0-0.1 mM; 10 min) is a strong inhibitor of protein biosynthesis in vitro as determined in a minimal E. coli purified system for poly(U)-directed poly(Phe) synthesis with an IC50 value of 0.4 μM[2]. |
| Molecular Formula | C56H55N15O10S6 |
|---|---|
| Molecular Weight | 1290.52000 |
| Exact Mass | 1289.26000 |
| PSA | 538.06000 |
| LogP | 7.60430 |
| InChIKey | JMDULECOHIXMNX-MZHFYNGJSA-N |
| SMILES | CNC(=O)CC1NC(=O)c2csc(n2)-c2ccc(-c3nc(C4=NC(C(=O)N5CCCC5C(N)=O)CO4)cs3)nc2-c2csc(n2)-c2csc(n2)C(C(O)c2ccccc2)NC(=O)CNC(=O)c2nc(sc2COC)C(C(C)C)NC(=O)c2nc1sc2C |