134861-34-0

134861-34-0 structure

Name: GE 2270A
Chemical Name: Mdl 62879
CAS Number: 134861-34-0
Molecular Formula: C₅₆H₅₅N₁₅O₁₀S₆
Molecular Weight: 1290.52000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-08-20 05:56:42
Modify Date: 2024-01-02 21:03:07
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2].

Name	Mdl 62879

Description	GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 0.4 μM (poly(U)-directed poly(Phe) synthesis)[2]
In Vitro	GE 2270A (0.01-100 mg/L) inhibits poly(U)-directed poly(Phe) synthesis in cell-free systems with an IC50 value of 0.12 mg/L[1]. GE 2270A (0-0.1 mM; 10 min) is a strong inhibitor of protein biosynthesis in vitro as determined in a minimal E. coli purified system for poly(U)-directed poly(Phe) synthesis with an IC50 value of 0.4 μM[2].