Lamivudine

Modify Date: 2025-08-20 08:44:24

Lamivudine structure	Common Name	Lamivudine
	CAS Number	134678-17-4	Molecular Weight	229.256
	Density	1.7±0.1 g/cm3	Boiling Point	475.4±55.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₁N₃O₃S	Melting Point	177 °C
	MSDS	Chinese USA	Flash Point	241.3±31.5 °C
	Symbol	GHS08	Signal Word	Warning

Use of Lamivudine

Lamivudine is a nucleoside reverse transcriptase inhibitors?(NRTIs). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus.

Name	lamivudine
Synonym	More Synonyms

Description	Lamivudine is a nucleoside reverse transcriptase inhibitors?(NRTIs). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Signaling Pathways >> Anti-infection >> Reverse Transcriptase Research Areas >> Infection
References	[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4.

Description

Lamivudine is a nucleoside reverse transcriptase inhibitors?(NRTIs). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus.

Related Catalog

Signaling Pathways >> Anti-infection >> HIV

Signaling Pathways >> Anti-infection >> Reverse Transcriptase

Research Areas >> Infection

References

[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551.

[2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4.

Density	1.7±0.1 g/cm3
Boiling Point	475.4±55.0 °C at 760 mmHg
Melting Point	177 °C
Molecular Formula	C₈H₁₁N₃O₃S
Molecular Weight	229.256
Flash Point	241.3±31.5 °C
Exact Mass	229.052109
PSA	115.67000
LogP	-0.71
Vapour Pressure	0.0±2.7 mmHg at 25°C
Index of Refraction	1.755
InChIKey	JTEGQNOMFQHVDC-NKWVEPMBSA-N
SMILES	Nc1ccn(C2CSC(CO)O2)c(=O)n1
Storage condition	Freezer

Lamivudine MSDS(Chinese)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H361
Precautionary Statements	P281
Hazard Codes	Xi
Risk Phrases	63
RIDADR	NONH for all modes of transport
RTECS	UW7361333
HS Code	2934999090

Precursor 6
CAS#:131086-21-0 Lamivudine CAS#:147027-10-9 (2R-CIS)-5-(4-A... CAS#:69-72-7 Salicylic acid CAS#:173522-96-8 Lamivudine sali...
CAS#:145985-97-3 cis-2-[[(tert-b... CAS#:1091585-31-7 (2R,5S)-5-(4'-a...
DownStream 1
CAS#:173522-96-8 Lamivudine sali...

HS Code	2938901000
Summary	HS: 2938901000. 4-amino-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1h)-one. VAT:17.0%. tax rebate rate:13.0%. supervision conditions:None. MFN tarrif:6.5%. general tariff:20.0%

Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.

Drug Metab. Dispos. 43(1) , 147-53, (2014)

This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

Quantitative mass spectrometry imaging of emtricitabine in cervical tissue model using infrared matrix-assisted laser desorption electrospray ionization.

Anal. Bioanal. Chem 407(8) , 2073-84, (2015)

A quantitative mass spectrometry imaging (QMSI) technique using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) is demonstrated for the antiretroviral (ARV) drug emtrici...

The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.

Environ. Mol. Mutagen. 54(4) , 268-80, (2013)

The events or factors that lead from normal cell function to conditions and diseases such as aging or cancer reflect complex interactions between cells and their environment. Cellular stress responses...

2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-

3TC

Heptodin

cent

(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

Lamivudine

Zeffix

Zefix

Hepitec

Heptivir

2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)

2',3'-Dideoxy-3'-thiacytidine

Heptovir

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

MFCD00869739

(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cystosine

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Epivir

4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

3&L-SddC

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Lamivudine
Price: Check
Purity: 98.0%
Delivery: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Lamivudine
Price: ￥168.0/50mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Lamivudine
Price: $200.0/100mg $400.0/250mg $800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Lamivudine
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: lamivudine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: ￥156/5g

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Lamivudine

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.