Galanthamine 10-Oxide(Galanthamine N-Oxide)

Modify Date: 2025-08-27 00:00:46

Galanthamine 10-Oxide(Galanthamine N-Oxide) structure	Common Name	Galanthamine 10-Oxide(Galanthamine N-Oxide)
	CAS Number	134332-50-6	Molecular Weight	303.35300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₁NO₄	Melting Point	246-247ºC
	MSDS	N/A	Flash Point	N/A

Use of Galanthamine 10-Oxide(Galanthamine N-Oxide)

Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].

Name	Galanthamine N-Oxide
Synonym	More Synonyms

Description	Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33. [2]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

Description

Related Catalog

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

References

[1]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

[2]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

Melting Point	246-247ºC
Molecular Formula	C₁₇H₂₁NO₄
Molecular Weight	303.35300
Exact Mass	303.14700
PSA	68.12000
LogP	1.82170
InChIKey	LROQBKNDGTWXET-CSBKYJRVSA-N
SMILES	COc1ccc2c3c1OC1CC(O)C=CC31CC[N+](C)([O-])C2

Hazard Codes	Xi

Galantamine

CAS#:357-70-0

Galanthamine 10...

CAS#:134332-50-6

Literature: Kobayashi, Shigeru; Satoh, Kimihito; Numata, Atsushi; Shingu, Tetsuro; Kihara, Masaru Phytochemistry (Elsevier), 1991 , vol. 30, # 2 p. 675 - 677

O-Desmethyl gal...

CAS#:60755-80-8

Galanthamine 10...

CAS#:134332-50-6

Literature: Phytochemistry (Elsevier), , vol. 30, # 2 p. 675 - 677

diazomethane

CAS#:186581-53-3

N/A

CAS#:134332-51-7

Galanthamine 10...

CAS#:134332-50-6

Literature: Kobayashi, Shigeru; Satoh, Kimihito; Numata, Atsushi; Shingu, Tetsuro; Kihara, Masaru Phytochemistry (Elsevier), 1991 , vol. 30, # 2 p. 675 - 677

Precursor 3
CAS#:357-70-0 Galantamine CAS#:60755-80-8 O-Desmethyl gal... CAS#:186581-53-3 diazomethane
DownStream 1
CAS#:41303-74-6 N-Desmethyl Gal...

Nivalin-oxide

(4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide

galanthamine-N-oxide

Galanthamine 10-Oxide

N-Oxide Galantamine

Galanthamine |A-N-oxide

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Galanthamine 10-Oxide(Galanthamine N-Oxide)

Use of Galanthamine 10-Oxide(Galanthamine N-Oxide)

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.