MC-Val-Ala-PBD

Modify Date: 2025-09-05 12:28:31

MC-Val-Ala-PBD Structure
MC-Val-Ala-PBD structure
Common Name MC-Val-Ala-PBD
CAS Number 1342820-51-2 Molecular Weight 1089.20000
Density N/A Boiling Point N/A
Molecular Formula C60H64N8O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Val-Ala-PBD


MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].

 Names

Name (S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-hexanamido)-3-methylbutanamido)propanoic acid

 MC-Val-Ala-PBD Biological Activity

Description MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].
Related Catalog
Target

Pyrrolobenzodiazepines

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.

 Chemical & Physical Properties

Molecular Formula C60H64N8O12
Molecular Weight 1089.20000
Exact Mass 1088.46000
PSA 236.17000
LogP 7.11240
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.