Mc-Val-Cit-PAB-Cl
Modify Date: 2024-01-10 19:56:16
Mc-Val-Cit-PAB-Cl structure
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Common Name | Mc-Val-Cit-PAB-Cl | ||
|---|---|---|---|---|
| CAS Number | 1639351-92-0 | Molecular Weight | 591.10 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H39ClN6O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mc-Val-Cit-PAB-ClMc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). |
| Name | Mc-Val-Cit-PAB-Cl |
|---|
| Description | Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). |
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| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Molecular Formula | C28H39ClN6O6 |
|---|---|
| Molecular Weight | 591.10 |
| Storage condition | -20°C |