Methyl 2-aminobenzoate

Modify Date: 2025-08-20 14:45:29

Methyl 2-aminobenzoate structure	Common Name	Methyl 2-aminobenzoate
	CAS Number	134-20-3	Molecular Weight	151.163
	Density	1.2±0.1 g/cm3	Boiling Point	256.0±0.0 °C at 760 mmHg
	Molecular Formula	C₈H₉NO₂	Melting Point	24 °C(lit.)
	MSDS	Chinese USA	Flash Point	104.4±0.0 °C
	Symbol	GHS07	Signal Word	Warning

Use of Methyl 2-aminobenzoate

Methyl anthranilate, a plant spice extract, is a quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria. Methyl anthranilate has been widely employed for the preparation of edible flavor and food additives in food processing industries[1].

Name	Methyl anthranilate
Synonym	More Synonyms

Description	Methyl anthranilate, a plant spice extract, is a quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria. Methyl anthranilate has been widely employed for the preparation of edible flavor and food additives in food processing industries[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	0.5 μL/mL of Methyl anthranilate evidently reduces biofilm formation (51.44%), swinging motility (74.86%), swarming motility (71.63%), protease activity (43.08%), and acyl-homoserine lactone (AHL) production. Methyl anthranilate might inhibit quorum sensing (QS) system in A. sobria by interfering with the biosynthesis of AHL, as well as competitively binding with receptor protein[1].
References	[1]. Tingting Li, et al. Methyl anthranilate: A novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria. Food Microbiol. 2020 Apr;86:103356.

Density	1.2±0.1 g/cm3
Boiling Point	256.0±0.0 °C at 760 mmHg
Melting Point	24 °C(lit.)
Molecular Formula	C₈H₉NO₂
Molecular Weight	151.163
Flash Point	104.4±0.0 °C
Exact Mass	151.063324
PSA	52.32000
LogP	2.04
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.566
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	slightly soluble

Methyl 2-aminobenzoate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB3325000

CHEMICAL NAME :: Anthranilic acid, methyl ester

CAS REGISTRY NUMBER :: 134-20-3

BEILSTEIN REFERENCE NO. :: 0606965

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C8-H9-N-O2

MOLECULAR WEIGHT :: 151.18

WISWESSER LINE NOTATION :: ZR BVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2910 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - coma

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2780 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 34800 mg/kg

SEX/DURATION :: male 8 day(s) pre-mating female 21 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 23 mg/disc

REFERENCE :: OIGZDE Osaka-shi Igakkai Zasshi. Journal of Osaka City Medical Association. (Osaka-shi Igakkai, c/o Osaka-shiritsu Daigaku Igakubu, 1-4-54 Asahi-cho, Abeno-ku, Osaka, 545, Japan) V.24- 1975- Volume(issue)/page/year: 34,267,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1207 No. of Facilities: 174 (estimated) No. of Industries: 3 No. of Occupations: 17 No. of Employees: 2956 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1207 No. of Facilities: 7048 (estimated) No. of Industries: 66 No. of Occupations: 71 No. of Employees: 104513 (estimated) No. of Female Employees: 49243 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	CB3325000
HS Code	2922499990

Precursor 10
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HS Code	2922439000
Summary	2922439000 anthranilic acid salts。supervision conditions:23(import license for dual-use item and technologies,export license for dual-use item and technologies)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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Synthesis and antibacterial activity of novel 4-chloro-2-mercaptobenzenesulfonamide derivatives.

J. Enzyme Inhib. Med. Chem. 28(1) , 41-51, (2013)

Few series of novel 4-chloro-2-mercaptobenzenesulfonamides have been synthesized by the reactions of N-(benzenesulfonyl)cyanamide potassium salts 7-15 with corresponding hydrazinecarbodithioic acid es...

High-performance liquid chromatographic determination of methyl anthranilate, hydroxymethylfurfural and related compounds in honey.

J. Chromatogr. A. 917(1-2) , 95-103, (2001)

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nerolioil,artifical

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EINECS 205-132-4

2-Aminobenzoic Acid Methyl Ester

Carbomethoxyaniline

FEMA 2682

Methyl anthranylate

methyl o-amino-benzoate

methyl anthranlate

Methyl anthanilate

2-methoxycarbonylaniline

Anthranilic Acid Methyl Ester

MFCD00007710

methyl 2-amino-benzoate

Methylaminobenzoate

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Methyl 2-aminobenzoate

NEROLI

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Nevoli oil

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