4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamate
Modify Date: 2024-01-21 14:48:12
4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamate structure
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Common Name | 4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamate | ||
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| CAS Number | 1338575-41-9 | Molecular Weight | 436.502 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 655.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C28H24N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 350.1±31.5 °C | |
Use of 4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamateWWL123 is a potent and selective ABHD6 inhibitor with an IC50 of 430 nM[1][2]. WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice[3]. |
| Name | 4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamate |
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| Synonym | More Synonyms |
| Description | WWL123 is a potent and selective ABHD6 inhibitor with an IC50 of 430 nM[1][2]. WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice[3]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 655.2±55.0 °C at 760 mmHg |
| Molecular Formula | C28H24N2O3 |
| Molecular Weight | 436.502 |
| Flash Point | 350.1±31.5 °C |
| Exact Mass | 436.178680 |
| LogP | 5.20 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.631 |
| 4'-Carbamoyl-3-biphenylyl (3-biphenylylmethyl)methylcarbamate |
| Carbamic acid, N-([1,1'-biphenyl]-3-ylmethyl)-N-methyl-, 4'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester |