Vazegepant

Modify Date: 2024-01-14 12:37:19

Vazegepant structure	Common Name	Vazegepant
	CAS Number	1337918-83-8	Molecular Weight	638.80
	Density	1.3±0.1 g/cm3	Boiling Point	933.7±65.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₄₆N₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	518.5±34.3 °C

Use of Vazegepant

Vazegepant is the first intranasal CGRP receptor antagonist for the study the acute research of migraine[1][2].

Name	N-{(2R)-3-(7-Methyl-1H-indazol-5-yl)-1-[4-(1-methyl-4-piperidinyl)-1-piperazinyl]-1-oxo-2-propanyl}-4-(2-oxo-1,2-dihydro-3-quinolinyl)-1-piperidinecarboxamide
Synonym	More Synonyms

Description	Vazegepant is the first intranasal CGRP receptor antagonist for the study the acute research of migraine[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CGRP Receptor Signaling Pathways >> Neuronal Signaling >> CGRP Receptor Research Areas >> Neurological Disease
References	[1]. Leonard KA, et al. Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2020 Mar 26;63(6):2915-2929. [2]. Gene M Dubowchik,Charles M Conway,Alison W Xin.Blocking the CGRP Pathway for Acute and Preventive Treatment of Migraine: The Evolution of Success.

Description

Vazegepant is the first intranasal CGRP receptor antagonist for the study the acute research of migraine[1][2].

Related Catalog

Signaling Pathways >> GPCR/G Protein >> CGRP Receptor

Signaling Pathways >> Neuronal Signaling >> CGRP Receptor

Research Areas >> Neurological Disease

References

[1]. Leonard KA, et al. Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2020 Mar 26;63(6):2915-2929.

[2]. Gene M Dubowchik,Charles M Conway,Alison W Xin.Blocking the CGRP Pathway for Acute and Preventive Treatment of Migraine: The Evolution of Success.

Density	1.3±0.1 g/cm3
Boiling Point	933.7±65.0 °C at 760 mmHg
Molecular Formula	C₃₆H₄₆N₈O₃
Molecular Weight	638.80
Flash Point	518.5±34.3 °C
Exact Mass	638.369263
LogP	4.30
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.648

1-Piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-N-[(1R)-1-[(7-methyl-1H-indazol-5-yl)methyl]-2-[4-(1-methyl-4-piperidinyl)-1-piperazinyl]-2-oxoethyl]-

N-{(2R)-3-(7-Methyl-1H-indazol-5-yl)-1-[4-(1-methyl-4-piperidinyl)-1-piperazinyl]-1-oxo-2-propanyl}-4-(2-oxo-1,2-dihydro-3-quinolinyl)-1-piperidinecarboxamide

DC Chemicals Limited
China
Product Name: Vazegepant
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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