AM 92016

Modify Date: 2025-11-29 00:04:49

AM 92016 Structure
AM 92016 structure
Common Name AM 92016
CAS Number 133229-11-5 Molecular Weight 483.84
Density N/A Boiling Point N/A
Molecular Formula C19H25Cl3N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AM 92016


AM 92016 (hydrochloride) is a specific IK inhibitor. AM 92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM[1].

 Names

Name AM-92016 hydrochloride

 AM 92016 Biological Activity

Description AM 92016 (hydrochloride) is a specific IK inhibitor. AM 92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM[1].
Related Catalog
References

[1]. ConnorsSP,etal.Actions and mechanisms of action of novel analogues of sotalol on guinea-pig and rabbitventricular cells. Br J Pharmacol. 1992 Aug;106(4):958-65.

 Chemical & Physical Properties

Molecular Formula C19H25Cl3N2O4S
Molecular Weight 483.84
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