Name | (3S)-3-[4-({4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]-3-(1,2-oxazol-3-yl)propanoic acid |
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Synonyms |
(3S)-3-[4-({4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]-3-(1,2-oxazol-3-yl)propanoic acid
3-Isoxazolepropanoic acid, β-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl]-, (βS)- |
Description | AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. |
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Related Catalog | |
Target |
EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1] |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 633.4±65.0 °C at 760 mmHg |
Molecular Formula | C24H19F3N2O4S |
Molecular Weight | 488.48 |
Flash Point | 336.9±34.3 °C |
Exact Mass | 488.101776 |
LogP | 5.27 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.583 |