AM 92016

Names

[ Name ]:
AM 92016

Biological Activity

[Description]:

AM 92016 (hydrochloride) is a specific IK inhibitor. AM 92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. ConnorsSP,etal.Actions and mechanisms of action of novel analogues of sotalol on guinea-pig and rabbitventricular cells. Br J Pharmacol. 1992 Aug;106(4):958-65.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₅Cl₃N₂O₄S

[ Molecular Weight ]:
483.84

Related Compounds

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