AM-6494
Names
[ CAS No. ]:
1874232-80-0
[ Name ]:
AM-6494
Biological Activity
[Description]:
AM-6494 is a potent and orally active BACE1 (efficacious β-site amyloid precursor protein cleaving enzyme 1) inhibitor (IC50=0.4 nM) with in vivo selectivity over BACE2 (IC50=18.6 nM)[1].
[Related Catalog]:
[Target]
IC50: (BACE1), 18.6 nM (BACE2)[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C22H21F2N5O3S
[ Molecular Weight ]:
473.50