rubrofusarin-6-glucoside

Modify Date: 2024-01-08 16:45:35

rubrofusarin-6-glucoside Structure
rubrofusarin-6-glucoside structure
Common Name rubrofusarin-6-glucoside
CAS Number 132922-80-6 Molecular Weight 434.39300
Density 1.558g/cm3 Boiling Point 734.8ºC at 760mmHg
Molecular Formula C21H22O10 Melting Point N/A
MSDS N/A Flash Point 260.2ºC

 Use of rubrofusarin-6-glucoside


Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC50 of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression[1].

 Names

Name 5-hydroxy-8-methoxy-2-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzo[g]chromen-4-one
Synonym More Synonyms

 rubrofusarin-6-glucoside Biological Activity

Description Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC50 of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression[1].
Related Catalog
Target

IC50: 87.36 μM (PTP1B)[1]

References

[1]. Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630.

 Chemical & Physical Properties

Density 1.558g/cm3
Boiling Point 734.8ºC at 760mmHg
Molecular Formula C21H22O10
Molecular Weight 434.39300
Flash Point 260.2ºC
Exact Mass 434.12100
PSA 159.05000
LogP 0.14750
Vapour Pressure 1.15E-22mmHg at 25°C
Index of Refraction 1.69

 Synonyms

Rubrofusarin-6-glucoside