rubrofusarin-6-glucoside

Names

[ Name ]:
rubrofusarin-6-glucoside

[Synonym ]:
Rubrofusarin-6-glucoside

Biological Activity

[Description]:

Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC50 of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

IC50: 87.36 μM (PTP1B)[1]

[References]

[1]. Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630.

Chemical & Physical Properties

[ Density]:
1.558g/cm3

[ Boiling Point ]:
734.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₂O₁₀

[ Molecular Weight ]:
434.39300

[ Flash Point ]:
260.2ºC

[ Exact Mass ]:
434.12100

[ PSA ]:
159.05000

[ LogP ]:
0.14750

[ Vapour Pressure ]:
1.15E-22mmHg at 25°C

[ Index of Refraction ]:
1.69

Related Compounds

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