Fluphenazine-d8 Dihydrochloride

Modify Date: 2025-08-26 17:12:15

Fluphenazine-d8 Dihydrochloride Structure
Fluphenazine-d8 Dihydrochloride structure
Common Name Fluphenazine-d8 Dihydrochloride
CAS Number 1323633-98-2 Molecular Weight 445.570843824
Density N/A Boiling Point N/A
Molecular Formula C22H18D8F3N3OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fluphenazine-d8 Dihydrochloride


Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2[1][2][3][4][5][6].

 Names

Name 2-[2,2,3,3,5,5,6,6-octadeuterio-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol

 Fluphenazine-d8 Dihydrochloride Biological Activity

Description Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2[1][2][3][4][5][6].
Related Catalog

 Chemical & Physical Properties

Molecular Formula C22H18D8F3N3OS
Molecular Weight 445.570843824
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