Description |
Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells[1].
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Related Catalog |
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In Vitro |
Quinaldopeptin is quite active against B16-F10 cells with IC50 values approximately 3-fold superior to that of chromomycin A3[1].
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In Vivo |
Quinaldopeptin shows slight prolongation of life-span in P388-bearing mice at 0.03~0.01 mg/kg, but the antitumor activities is quite limited[1].
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References |
[1]. S Toda, et al. Quinaldopeptin, a novel antibiotic of the quinomycin family. J Antibiot (Tokyo). 1990 Jul;43(7):796-808.
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