130743-07-6

130743-07-6 structure

Name: Quinaldopeptin
Chemical Name: Quinaldopeptin
CAS Number: 130743-07-6
Molecular Formula: C₆₂H₇₈N₁₄O₁₄
Molecular Weight: 1243.37000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-05-24 13:14:32
Modify Date: 2025-09-21 12:07:07
Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells[1].

Name	Quinaldopeptin
Synonyms	caazacyclodotriacontin-19-yl)-2-quinolinecarboxamide

Description	Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Quinaldopeptin is quite active against B16-F10 cells with IC50 values approximately 3-fold superior to that of chromomycin A3[1].
In Vivo	Quinaldopeptin shows slight prolongation of life-span in P388-bearing mice at 0.03~0.01 mg/kg, but the antitumor activities is quite limited[1].
References	[1]. S Toda, et al. Quinaldopeptin, a novel antibiotic of the quinomycin family. J Antibiot (Tokyo). 1990 Jul;43(7):796-808.