5-Chloro-8-hydroxyquinoline

Modify Date: 2024-01-02 19:47:13

5-Chloro-8-hydroxyquinoline Structure
5-Chloro-8-hydroxyquinoline structure
Common Name 5-Chloro-8-hydroxyquinoline
CAS Number 130-16-5 Molecular Weight 179.603
Density 1.4±0.1 g/cm3 Boiling Point 348.7±22.0 °C at 760 mmHg
Molecular Formula C9H6ClNO Melting Point 122-124 °C(lit.)
MSDS Chinese USA Flash Point 164.7±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 5-Chloro-8-hydroxyquinoline


Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis drug.

 Names

Name 5-Chloro-8-hydroxyquinoline
Synonym More Synonyms

 5-Chloro-8-hydroxyquinoline Biological Activity

Description Cloxiquine is an antibacterial, antifungal, antiaging and antituberculosis drug.
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 348.7±22.0 °C at 760 mmHg
Melting Point 122-124 °C(lit.)
Molecular Formula C9H6ClNO
Molecular Weight 179.603
Flash Point 164.7±22.3 °C
Exact Mass 179.013794
PSA 33.12000
LogP 3.02
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.697

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VC4590000
CHEMICAL NAME :
8-Quinolinol, 5-chloro-
CAS REGISTRY NUMBER :
130-16-5
BEILSTEIN REFERENCE NO. :
0005289
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H6-Cl-N-O
MOLECULAR WEIGHT :
179.61
WISWESSER LINE NOTATION :
T66 BNJ GG JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
1 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 307,141,1994

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS VC4590000
HS Code 2933499090

 Synthetic Route

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

J. Med. Chem. 54 , 591-602, (2011)

Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced...

Photoluminescence and thermoanalytical studies of complexes based on 5-Cl-8-hydroxyquinoline and calix[4]arene ligands.

Mater. Sci. Eng. C. Mater. Biol. Appl. 33(4) , 2213-20, (2013)

A innovative 5-Cl-8-oxyquinolinepropoxycalix[4]arene ligand (2) have been prepared, exhibiting, at room temperature, blue fluorescent light emission and resulting in shift band to green fluorescent li...

Poly(L-lactide) and poly(butylene succinate) immiscible blends: from electrospinning to biologically active materials.

Mater. Sci. Eng. C. Mater. Biol. Appl. 41 , 119-26, (2014)

For the first time the preparation of defect-free fibers from immiscible blends of high molar mass poly(lactic acid) (PLA) and poly(butylene succinate) (PBS) in the whole range of the polyester weight...

 Synonyms

5-Chloro-8-hydroxy quinoline
5-chloroquinolin-8-ol
5-Chloroquinophenol
cloxiquine
5-Chlorooxine
EINECS 204-978-1
5-Chloro-8-quinolinol
5-Chloro-8-hydroxyquinoline
5-Chloro-quinolin-8-ol
8-Quinolinol, 5-chloro-
Dermofungin
quinolin-8-ol, 5-chloro-
5-Chloro-8-oxyquinoline
MFCD00006788
5-Chloro-8-oxychinolin
cloxyquin
5-CHLORO-8-HYDROXY-QUINOLINE