PKSI-527

Modify Date: 2024-01-31 12:10:31

PKSI-527 structure	Common Name	PKSI-527
	CAS Number	128837-71-8	Molecular Weight	473.99
	Density	N/A	Boiling Point	763.1ºC at 760mmHg
	Molecular Formula	C₂₅H₃₂ClN₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	415.3ºC

Use of PKSI-527

PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1].

Name	2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]acetic acid,hydrochloride
Synonym	More Synonyms

Description	PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Inflammation/Immunology
References	[1]. Fujimori Y, et al. Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice. Agents Actions. 1993 May;39(1-2):42-8.

Boiling Point	763.1ºC at 760mmHg
Molecular Formula	C₂₅H₃₂ClN₃O₄
Molecular Weight	473.99
Flash Point	415.3ºC
Exact Mass	473.20800
PSA	125.01000
LogP	5.16040
Vapour Pressure	1.74E-24mmHg at 25°C

H-Tra-L-Phe-4-carboxymethylanilide hydrochloride

Pksi 527

PKSI-0527

C25H31N3O4.HCl

t-AMCHA-Phe-p-APAA

PKSI-527

Use of PKSI-527

Names

PKSI-527 Biological Activity

Chemical & Physical Properties

Synonyms