5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate
Modify Date: 2024-01-20 18:35:13
5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate structure
|
Common Name | 5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate | ||
|---|---|---|---|---|
| CAS Number | 127770-45-0 | Molecular Weight | 529.279 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 743.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C25H14Cl2O9 | Melting Point | 210ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 403.3±32.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess ROS generation within human neuronal-glial (HNG) cells in primary co-culture[1] |
| Name | 5(6)-carboxy-2',7'-dichlorofluorescein diacetate |
|---|---|
| Synonym | More Synonyms |
| Description | 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess ROS generation within human neuronal-glial (HNG) cells in primary co-culture[1] |
|---|---|
| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 743.3±60.0 °C at 760 mmHg |
| Melting Point | 210ºC (dec.)(lit.) |
| Molecular Formula | C25H14Cl2O9 |
| Molecular Weight | 529.279 |
| Flash Point | 403.3±32.9 °C |
| Exact Mass | 528.001465 |
| PSA | 125.43000 |
| LogP | 3.66 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.712 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
|
A high throughput in vitro mrp2 assay to predict in vivo biliary excretion.
Xenobiotica 42 , 157-163, (2012) Prediction of biliary excretion is a challenge for drug discovery scientists due to the lack of in vitro assays. This study explores the possibility of establishing a simple assay to predict in vivo b... |
|
|
Impact of probe compound in MRP2 vesicular transport assays.
Eur. J. Pharm. Sci. 46 , 100-105, (2012) MRP2 is an efflux transporter that is expressed mainly in the canalicular membrane of hepatocytes, where it expels polar and ionic compounds into the bile. MRP2 is also present in the apical membrane ... |
|
|
Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle.
J. Cell Biol. 111 , 877, (1990) vps3 mutants of the yeast Saccharomyces cerevisiae are impaired in the sorting of newly synthesized soluble vacuolar proteins and in the acidification of the vacuole (Rothman, J. H., and T. H. Stevens... |
| 5-(6)-CDCFDA [5(6)-Carboxy-2',7'-dichlorofluorescein Diacetate] |
| Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-bis(acetyloxy)-2',7'-dichloro-3-oxo- |
| 3',6'-Diacetoxy-2',7'-dichloro-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid |