18:1 DAP

Modify Date: 2024-01-05 11:45:10

18:1 DAP structure	Common Name	18:1 DAP
	CAS Number	127512-29-2	Molecular Weight	648.05400
	Density	0.916g/cm3	Boiling Point	670.148ºC at 760 mmHg
	Molecular Formula	C₄₁H₇₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	359.092ºC

Use of 18:1 DAP

DODAP is a cationic lipid. The ionizable lipid DODAP is a lipid component of the liposome. DODAP can be used to encapsulate siRNA, immunostimulatory chemotherapeutic agents for in vitro and in vivo delivery and so on[1][2][3].

Name	1,2-Dioleoyloxy-3-(dimethylamino)propane
Synonym	More Synonyms

Description	DODAP is a cationic lipid. The ionizable lipid DODAP is a lipid component of the liposome. DODAP can be used to encapsulate siRNA, immunostimulatory chemotherapeutic agents for in vitro and in vivo delivery and so on[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Dabbas S, et al. Importance of the liposomal cationic lipid content and type in tumor vascular targeting: physicochemical characterization and in vitro studies using human primary and transformed endothelial cells. Endothelium. 2008;15(4):189-201. [2]. Hamzah J, et al. Targeted liposomal delivery of TLR9 ligands activates spontaneous antitumor immunity in an autochthonous cancer model. J Immunol. 2009;183(2):1091-1098. [3]. Liu Q, et al. Biotinylated cyclen-contained cationic lipids as non-viral gene delivery vectors. Chem Biol Drug Des. 2013;82(4):376-383.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Dabbas S, et al. Importance of the liposomal cationic lipid content and type in tumor vascular targeting: physicochemical characterization and in vitro studies using human primary and transformed endothelial cells. Endothelium. 2008;15(4):189-201.

[2]. Hamzah J, et al. Targeted liposomal delivery of TLR9 ligands activates spontaneous antitumor immunity in an autochthonous cancer model. J Immunol. 2009;183(2):1091-1098.

[3]. Liu Q, et al. Biotinylated cyclen-contained cationic lipids as non-viral gene delivery vectors. Chem Biol Drug Des. 2013;82(4):376-383.

Density	0.916g/cm3
Boiling Point	670.148ºC at 760 mmHg
Molecular Formula	C₄₁H₇₇NO₄
Molecular Weight	648.05400
Flash Point	359.092ºC
Exact Mass	647.58500
PSA	55.84000
LogP	12.07800
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.476