FBPase-IN-2

Modify Date: 2025-08-25 18:06:51

FBPase-IN-2 Structure
FBPase-IN-2 structure
Common Name FBPase-IN-2
CAS Number 127143-25-3 Molecular Weight 228.59
Density N/A Boiling Point N/A
Molecular Formula C8H5ClN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FBPase-IN-2


FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].

 Names

Name FBPase-IN-2

 FBPase-IN-2 Biological Activity

Description FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].
Related Catalog
Target

IC50: 0.15 μM (FBPase)[1]

References

[1]. Han X, et al. Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase. Bioorg Med Chem. 2020 Sep 15;28(18):115624.

 Chemical & Physical Properties

Molecular Formula C8H5ClN2O4
Molecular Weight 228.59
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