FBPase-IN-2

Names

[ CAS No. ]:
127143-25-3

[ Name ]:
FBPase-IN-2

Biological Activity

[Description]:

FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

IC50: 0.15 μM (FBPase)[1]


[References]

[1]. Han X, et al. Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase. Bioorg Med Chem. 2020 Sep 15;28(18):115624.

Chemical & Physical Properties

[ Molecular Formula ]:
C8H5ClN2O4

[ Molecular Weight ]:
228.59

Related Compounds

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