NMS-P515

Modify Date: 2024-04-05 18:58:29

NMS-P515 Structure
NMS-P515 structure
Common Name NMS-P515
CAS Number 1262395-13-0 Molecular Weight 355.47
Density N/A Boiling Point N/A
Molecular Formula C21H29N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NMS-P515


NMS-P515 is a potent and stereospecific PARP-1 inhibitor, with an IC50 of 27 nM in hela cells. Anti-tumor activity[1].

 Names

Name NMS-P515

 NMS-P515 Biological Activity

Description NMS-P515 is a potent and stereospecific PARP-1 inhibitor, with an IC50 of 27 nM in hela cells. Anti-tumor activity[1].
Related Catalog
Target

PARP-1:27 nM (IC50, in hela cells)

References

[1]. Papeo G, et al. Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. ACS Med Chem Lett. 2019 Mar 13;10(4):534-538.

 Chemical & Physical Properties

Molecular Formula C21H29N3O2
Molecular Weight 355.47