c-Fms-IN-8

Modify Date: 2024-01-09 15:10:06

Use of c-Fms-IN-8

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].

Name	c-Fms-IN-8

Description	c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
Target	IC50: 9.1 nM (CSF-1R)[1].
References	[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

Molecular Formula	C₂₇H₃₀N₂O₅
Molecular Weight	462.54