TM 38837
Modify Date: 2025-08-22 12:00:08
TM 38837 structure
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Common Name | TM 38837 | ||
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| CAS Number | 1253641-65-4 | Molecular Weight | 617.512 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C30H25Cl2F3N4OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TM 38837TM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. TM38837 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. TM38837 reduces propensity for psychiatric side effects[1][2]. |
| Name | TM-38837 |
|---|---|
| Synonym | More Synonyms |
| Description | TM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist. TM38837 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effects. TM38837 reduces propensity for psychiatric side effects[1][2]. |
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| Related Catalog | |
| Target |
CB1 |
| In Vivo | TM38837 (10-100 mg/kg; p.o.) induces a significant increase in freezing behavior at 100 mg/kg[1]. Animal Model: 7-8 weeks old male C57BL/6 N mice (B6N)[1] Dosage: 10, 30, or 100 mg/kg Administration: p.o. Result: High dose (100 mg/kg) induced a significant increase in freezing behavior. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C30H25Cl2F3N4OS |
| Molecular Weight | 617.512 |
| Exact Mass | 616.107849 |
| LogP | 8.91 |
| Index of Refraction | 1.635 |
| 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]- |
| 1-(2,4-Dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-5-(5-{[4-(trifluoromethyl)phenyl]ethynyl}-2-thienyl)-1H-pyrazole-3-carboxamide |
| TM-38837 |