KS 176
Modify Date: 2024-01-02 14:14:28
KS 176 structure
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Common Name | KS 176 | ||
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| CAS Number | 1253452-78-6 | Molecular Weight | 405.40300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H19N3O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of KS 176KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference. |
| Name | N-(4-(2-hydroxyethyl)phenyl)-2-(4-nitrobenzamido)benzamide |
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| Synonym | More Synonyms |
| Description | KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference. |
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| Related Catalog | |
| References |
| Molecular Formula | C22H19N3O5 |
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| Molecular Weight | 405.40300 |
| Exact Mass | 405.13200 |
| PSA | 124.25000 |
| LogP | 4.30340 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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| KS176 |