KS-99
Modify Date: 2024-01-06 21:08:56
KS-99 structure
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Common Name | KS-99 | ||
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| CAS Number | 1344698-28-7 | Molecular Weight | 466.147 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H10Br2N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KS-99KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization; interacts directly with the catalytic domain of BTK and inhibits phosphorylation at the Y223 residue and kinase activities; reduces the cell viability of MM and CD138+ cells (IC50=0.5-1 uM); inhibits the in vivo tumor growth of MM cells through the inhibition of BTK and tubulin. |
| Name | KS-99 |
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| Description | KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization; interacts directly with the catalytic domain of BTK and inhibits phosphorylation at the Y223 residue and kinase activities; reduces the cell viability of MM and CD138+ cells (IC50=0.5-1 uM); inhibits the in vivo tumor growth of MM cells through the inhibition of BTK and tubulin. |
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| References | References 1. Pandey MK, et al. Exp Hematol. 2017 Jun 22. pii: S0301-472X(17)30233-3. View Related Products by Target BTK |
| Molecular Formula | C17H10Br2N2O2S |
|---|---|
| Molecular Weight | 466.147 |