KS-99
Names
[ CAS No. ]:
1344698-28-7
[ Name ]:
KS-99
Biological Activity
[Description]:
KS-99 (KS99) is a novel dual inhibitor of BTK and tubulin polymerization; interacts directly with the catalytic domain of BTK and inhibits phosphorylation at the Y223 residue and kinase activities; reduces the cell viability of MM and CD138+ cells (IC50=0.5-1 uM); inhibits the in vivo tumor growth of MM cells through the inhibition of BTK and tubulin.
[References]
References 1. Pandey MK, et al. Exp Hematol. 2017 Jun 22. pii: S0301-472X(17)30233-3. View Related Products by Target BTK
Chemical & Physical Properties
[ Molecular Formula ]:
C17H10Br2N2O2S
[ Molecular Weight ]:
466.147