3’-Deoxy-3’-fluoro-xyloguanosine

Modify Date: 2024-01-10 09:19:46

3’-Deoxy-3’-fluoro-xyloguanosine Structure
3’-Deoxy-3’-fluoro-xyloguanosine structure
Common Name 3’-Deoxy-3’-fluoro-xyloguanosine
CAS Number 125291-15-8 Molecular Weight 285.23
Density 2.17g/cm3 Boiling Point 726.1ºC at 760mmHg
Molecular Formula C10H12FN5O4 Melting Point N/A
MSDS N/A Flash Point 392.9ºC

 Use of 3’-Deoxy-3’-fluoro-xyloguanosine


3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-amino-9-[(2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonym More Synonyms

 3’-Deoxy-3’-fluoro-xyloguanosine Biological Activity

Description 3’-Deoxy-3’-fluoro-xyloguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.17g/cm3
Boiling Point 726.1ºC at 760mmHg
Molecular Formula C10H12FN5O4
Molecular Weight 285.23
Flash Point 392.9ºC
Exact Mass 285.08700
PSA 140.27000
Vapour Pressure 3.94E-22mmHg at 25°C
Index of Refraction 1.876

 Synthetic Route

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3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Gosselin; Puech; Genu-Dellac; Imbach Carbohydrate Research, 1993 , vol. 249, # 1 p. 1 - 17

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Puech, Frederic; Gosselin, Gilles; Imbach, Jean-Louis Tetrahedron Letters, 1989 , vol. 30, # 24 p. 3171 - 3174

~%

3’-Deoxy-3’-fluoro-xyloguanosine Structure

3’-Deoxy-3’-flu...

CAS#:125291-15-8

Literature: Puech, Frederic; Gosselin, Gilles; Imbach, Jean-Louis Tetrahedron Letters, 1989 , vol. 30, # 24 p. 3171 - 3174

 Synonyms

dF.b.XG
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