BCI

Modify Date: 2024-01-11 10:01:51

BCI structure	Common Name	BCI
	CAS Number	1245792-51-1	Molecular Weight	317.424
	Density	1.2±0.1 g/cm3	Boiling Point	484.6±45.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₃NO	Melting Point	N/A
	MSDS	N/A	Flash Point	161.3±28.9 °C

Use of BCI

BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5[1].

Name	(2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone
Synonym	More Synonyms

Description	BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
References	[1]. Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45.

Density	1.2±0.1 g/cm3
Boiling Point	484.6±45.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₃NO
Molecular Weight	317.424
Flash Point	161.3±28.9 °C
Exact Mass	317.177979
LogP	5.65
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.625

Hazard Codes	Xi

(2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone

1H-Inden-1-one, 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)-

MFCD20232928

DC Chemicals Limited
China
Product Name: BCI
Price: $550.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥838/10 mM * 1 mL in DMSO

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BCI

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