BCI-137
Modify Date: 2025-09-27 11:04:35
BCI-137 structure
|
Common Name | BCI-137 | ||
|---|---|---|---|---|
| CAS Number | 112170-24-8 | Molecular Weight | 313.286 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C11H11N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BCI-137BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM; displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4. |
| Name | N-[(2,3-Dioxo-1,2,3,4-tetrahydro-6-quinoxalinyl)sulfonyl]alanine |
|---|---|
| Synonym | More Synonyms |
| Description | BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM; displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4. |
|---|---|
| References | References 1. Masciarelli S, et al. ACS Chem Biol. 2014 Aug 15;9(8):1674-9. View Related Products by Target Other Targets |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C11H11N3O6S |
| Molecular Weight | 313.286 |
| Exact Mass | 313.036865 |
| LogP | -1.30 |
| Index of Refraction | 1.612 |
| InChIKey | VMSRTLYZOWBBFW-UHFFFAOYSA-N |
| SMILES | CC(NS(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1)C(=O)O |
| N-[(2,3-Dioxo-1,2,3,4-tetrahydro-6-quinoxalinyl)sulfonyl]alanine |
| Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]- |
| MFCD05148320 |