5-CFDA,AM
Modify Date: 2025-08-25 15:18:45
5-CFDA,AM structure
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Common Name | 5-CFDA,AM | ||
|---|---|---|---|---|
| CAS Number | 124412-00-6 | Molecular Weight | 532.45200 | |
| Density | 1.51g/cm3 | Boiling Point | 737ºC at 760mmHg | |
| Molecular Formula | C28H20O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 312.7ºC | |
Use of 5-CFDA,AM5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1]. |
| Name | acetyloxymethyl 3',6'-diacetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | 5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1]. |
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| Related Catalog | |
| References |
| Density | 1.51g/cm3 |
|---|---|
| Boiling Point | 737ºC at 760mmHg |
| Molecular Formula | C28H20O11 |
| Molecular Weight | 532.45200 |
| Flash Point | 312.7ºC |
| Exact Mass | 532.10100 |
| PSA | 140.73000 |
| LogP | 3.78260 |
| Vapour Pressure | 1.39E-21mmHg at 25°C |
| Index of Refraction | 1.655 |
| InChIKey | YDBUJZYYYBVSEF-UHFFFAOYSA-N |
| SMILES | CC(=O)OCOC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(OC(C)=O)cc2Oc2cc(OC(C)=O)ccc21 |
| 5-CFDA,AM |
| CFDA-AM |
| acetoxymethyl ester |
| 5-Carboxyfluorescein diacetate acetoxymethyl ester |
| 5-carboxyfluorescein diacetate |