Kobophenol A structure
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Common Name | Kobophenol A | ||
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| CAS Number | 124027-58-3 | Molecular Weight | 924.94100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C56H44O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Kobophenol AKobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 µM[1][2]. |
| Name | 5-[(2S,3R,4S,5S)-4-[(2S,3S)-3-[(2R,3R)-3-(3,5-dihydroxyphenyl)-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-2,5-bis(4-hydroxyphenyl)oxolan-3-yl]benzene-1,3-diol |
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| Synonym | More Synonyms |
| Description | Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 µM[1][2]. |
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| Related Catalog | |
| References |
[2]. Xu G, Zhang LP, Chen LF, Hu CQ. Yao Xue Xue Bao. 1994;29(11):818-822. |
| Molecular Formula | C56H44O13 |
|---|---|
| Molecular Weight | 924.94100 |
| Exact Mass | 924.27800 |
| PSA | 229.99000 |
| LogP | 10.65400 |
| Hazard Codes | Xn |
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| C6H4NO2.K |
| K-nicotinate |
| 3-Pyridinecarboxylic acid,potassium salt |
| Nicotinic acid,potassium salt |
| kobophenol A |
| Potassium nicotinate |
| (2S,2'R,3S,3'R)-3'-(3,5-dihydroxyphenyl)-4-[(2S,3S,4R,5S)-4-(3,5-dihydroxyphenyl)tetrahydro-2,5-bis(4-hydroxyphenyl)-3-furanyl]-2,2',3,3'-tetrahydro-2,2'-bis(4-hydroxyphenyl)-[3,4'-bibenzofuran]-6,6'-diol |
| Niacin Potassium Salt |
| Potassium 3-pyridinecarboxylate |