Isoborneol

Modify Date: 2024-01-02 16:11:58

Isoborneol structure	Common Name	Isoborneol
	CAS Number	124-76-5	Molecular Weight	154.249
	Density	1.0±0.1 g/cm3	Boiling Point	212.0±0.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₈O	Melting Point	208-214ºC
	MSDS	Chinese USA	Flash Point	65.6±0.0 °C
	Symbol	GHS02, GHS07	Signal Word	Danger

Use of Isoborneol

Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1)[1][2].

Name	DL-Isoborneol
Synonym	More Synonyms

Description	Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1)[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection Research Areas >> Neurological Disease
Target	HSV-1
In Vitro	Isoborneol ((±)-Isoborneol) protects against 6-OHDA-induced increases in caspase-3 activity and cytochrome C translocation into the cytosol from mitochondria. Isoborneol prevents 6-OHDA from decreasing the Bax/Bcl-2 ratio[1].
References	[1]. Tian LL, Zhou Z, Zhang Q, et al. Protective effect of (+/-) isoborneol against 6-OHDA-induced apoptosis in SH-SY5Y cells. Cell Physiol Biochem. 2007;20(6):1019‐1032. [2]. Armaka M, Papanikolaou E, Sivropoulou A, Arsenakis M. Antiviral properties of isoborneol, a potent inhibitor of herpes simplex virus type 1. Antiviral Res. 1999;43(2):79‐92.

Density	1.0±0.1 g/cm3
Boiling Point	212.0±0.0 °C at 760 mmHg
Melting Point	208-214ºC
Molecular Formula	C₁₀H₁₈O
Molecular Weight	154.249
Flash Point	65.6±0.0 °C
Exact Mass	154.135757
PSA	20.23000
LogP	2.71
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.502
Water Solubility	insoluble

Isoborneol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NP7300000

CHEMICAL NAME :: Isoborneol, DL-

CAS REGISTRY NUMBER :: 124-76-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H18-O

MOLECULAR WEIGHT :: 154.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,531,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,531,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03209

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,531,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0371 No. of Facilities: 1136 (estimated) No. of Industries: 3 No. of Occupations: 12 No. of Employees: 13463 (estimated) No. of Female Employees: 8811 (estimated)

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H228-H315
Precautionary Statements	P210
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	F;Xi
Risk Phrases	R11
Safety Phrases	S24/25
RIDADR	UN1325 4.1/PG 2
WGK Germany	2
RTECS	NP7300000
Hazard Class	4.1
HS Code	2906199090

Precursor 10
CAS#:464-49-3 (+)-Camphor CAS#:130979-66-7 (1R,2S,4R)-2-et... CAS#:64-17-5 Ethanol CAS#:28974-17-6 (1R)-2-exo-acet...
CAS#:565-00-4 Camphene CAS#:76-22-2 (+/-)-Camphor CAS#:6627-72-1 DL-2-Bornanol CAS#:24393-70-2 2-methylisoborneol
CAS#:464-43-7 (+)-Borneol CAS#:555-31-7 Aluminium isopr...
DownStream 2
CAS#:76-22-2 (+/-)-Camphor CAS#:464-49-3 (+)-Camphor

HS Code	2906199090
Summary	2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1R,2S,4R)-

exo-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

2-Hydroxybornane

Borneol

)-Isoborneol

EINECS 204-712-4

bornyl alcohol

Baros camphor

MFCD00074821

endo-borneol

(1R,2S,4R)-(+)-Borneol

(+)-Bornyl alcohol

UNII:M89NIB437X

(1R,2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

Bhimsaim camphor

d-borneol

2-Hydroxycamphane

Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-

1,7,7-Trimethylbicyclo(2.2.1)heptan-2-ol

Dryobalanops camphor

Bicyclo(2.2.1)heptan-2-ol, 1,7,7-trimethyl-

1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

Borneo camphor

(1R,2S,4R)-borneol

(1R-endo)-1,7,7-Trimethylbicyclo(2.2.1)heptan-2-ol

Camphol

Camphane, 2-hydroxy-

Malayan camphor

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Isoborneol
Price: ￥248.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: DL-Isoborneol
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isoborneol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 124-76-5 DL-Isoborneol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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